An approved reliable method for skin rejuvenation and volume enhancement is the injection of fillers into the skin.

The main structure of the human face consists of four main parts: skin, fat, muscle and bone. As we age, approximately from the age of twenty-five, collagen and elastin protein production in the skin begins to decrease. This causes the skin to lose elasticity and the volume of muscle and fat tissue to decrease. As a result, signs of aging and wrinkles become more pronounced.

Although experts have different opinions on collagen loss, it is generally accepted that aging begins around the age of 25. By this age, the level of collagen and elastin in the skin decreases by about 2% per year, which means that the skin has almost completely stopped producing collagen. Above this age, fillers can help the skin maintain beauty and youth. However, it is important to note that the FDA (United States Food and Drug Administration) states that the age for using skin fillers is for adults over 21 years of age (except for people with certain health conditions).

Fillers are used to restore lost tissue and skin volume or to create it in areas that are genetically deficient in volume. For example, they help to correct areas such as the lips or cheekbones, or to remove scars and acne scars. As a result, the face takes on a more beautiful and attractive appearance.

After explaining the use of fillers and their role in enhancing the beauty of the face and preserving youth, we will examine the nature of fillers and the types of fillers.

-Types of fillers in terms of durability:

1. Short-term – effective for several months
2. Medium-term – Effective for one year
3. Long-term – Effective for several years

Some fillers can be called permanent, but none of the different types of fillers have a permanent effect, but they have long-term effects, and of course the fact that fillers are not permanent is one of the positive points, because it is important to think about future changes before making permanent changes to the skin, and permanent substances can lead to negative consequences in the body.

The types of fillers vary according to the materials they are made of and their intended use.

1. Hyaluronic Acid (HA) Fillers

Hyaluronic acid filler is a slippery and sticky substance that is naturally produced in the body. If you want to reduce lines and wrinkles on your face, hyaluronic acid is a good option because it is found in every living organism. In the human body, this substance acts as a network that carries essential nutrients and moisturizer to the cells of the skin. Hyaluronic acid is used to increase the skin’s natural moisture and rejuvenate the skin. Hyaluronic acid filler is a transparent substance and is available as ready-made injection needles of skin fillers, each type of which is injected into a specific area. For example, the hyaluronic acid filler used to add volume to the under-eye areas is different from the hyaluronic acid filler used to add volume to the lips. The exact uses of hyaluronic acid filler are as follows:

– Treatment of acne scars and acne spots
– Cheekbone correction
– Removal of crow’s feet and wrinkles around the eyes
– Correction of smile lines and nasolabial lines
– Correction of interbrow lines and wrinkles between the eyebrows
– Removal of lines in the corners of the mouth, known as marionette lines
– Correction of lip borders and cigarette lines
– Elimination of lines on the forehead called worry lines

Injecting hyaluronic acid filler does not cause many side effects if done by an experienced doctor, and if possible side effects occur, an enzyme “hyaluronate” can be used to eliminate the filler. Hyaluronic acid fillers are not of animal origin. The strength of such fillers usually varies between six and twelve months, and re-injection may be required after this period.

2. Calcium Hydroxyapatite (CAA) Fillers

Calcium hydroxyapatite is one of the types of injectable fillers that is composed of very small and microscopic materials, and this substance provides more binding than any of the skin fillers. Therefore, the effect of this type of filler lasts longer and can sometimes be used in combination with other fillers such as hyaluronic acid. This filler is derived from hydroxyapatite, a type of mineral substance found naturally in the bones in our body, and is one of the densest among skin fillers. Calcium hydroxyapatite stimulates natural collagen production and is often used for the removal of medium to deep wrinkles and lines. It is approved by the FDA. This type of filler usually lasts for a year or more.

Please note that it is important to seek advice from a professional doctor for any medical prose or skin treatment.

3- Polymethyl Methylate (EMMA) Fillers

EMMA is one of the types of fillers with large particles and is almost permanent and can remain effective for five years after injection. This type of artificial substance provides a natural fit. EMMA not only fills empty lines in the skin, but can also stimulate collagen production in the injected area. One of the disadvantages of this filler is that it requires large amounts of filler to increase the volume and can take up to three months for its effects to appear, and there is a possibility that it may look like a small ball under the skin after injection.

Given the long-term effect of this substance, doctors do not prefer EMMA to treat different areas of the face. EMMA fillers have more side effects than short-term fillers, and there may be a risk of bruising and infection in the injected area.

4- Po lactic Acid (ELLA) Fillers

PLEA, like PMA, is an artificial and environmentally friendly substance that is biodegradable. This type of filler is injected into the skin to replace fat lost from the face. Po lactic acid is a collagen-producing substance and encourages the body to produce its own collagen at the injection site. This type of filler is effective in treating wrinkles and lines, especially in semi-lower facial areas such as laugh lines, sadness lines and lip volume enhancement. PLL A injection is performed monthly for three or four sessions and usually stimulates collagen production at the injection site, helping to smooth the skin surface.

This type of filler injection may need to be repeated at one-month intervals to maintain the results. This filler has a semi-permanent and multi-year effect and the filler itself dissolves a few days after the injection, but the effect persists.

5- Polyacrylamide Fillers

Polyacrylamide is one of the semi-permanent and collagen-producing fillers usually used by plastic surgeons to smooth deep wrinkles, correct the nose, define cheekbones and restore volume lost due to aging. This type of filler shows a minimal reaction with the human body and is considered biocompatible, so no sensitivity testing is needed. Once injected, Polyacrylamide produces collagen in the surrounding area, completely surrounding itself with a collagen layer. It may be necessary to use and inject large amounts of product to achieve the target with this filler.

6- Fat Cells

This is a less invasive method where body fat is usually removed by liposuction or other techniques and injected into different parts of the body and face. Although this method requires drugs, infection may occur in the area where fat is removed and fat is transferred, and the recovery time is long, it is one of the safest methods. Because the injected substance is extracted from the patient’s own body, which significantly reduces sensitivity to fillers.

Who Are Fillers Not Suitable for?

Although adding volume to the body with fillers is generally considered a low-risk and less invasive method, there are still people who are not suitable for this procedure. People with special health problems such as nerve and muscle diseases, bleeding disorders, diseases that cause cellular growth and proliferation disorders, and hypersensitivity to chemical substances should only use fillers with the approval of the relevant doctor. In addition, people who are pregnant or breastfeeding should never use any filler treatment method.
In general, healthy individuals without special health problems and who do not use chemical substances for skin treatment are the best candidates for the use of fillers in the face and body.